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1

Removal of chloroform from biodegradable therapeutic microspheres by radiolysis

S.W. Zielhuis, J.F.W. Nijsen, L. Dorland, G.C. Krijger, A.D. van het Schip, W.E. Hennink

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 295 KB

english, 2006

2

Neutron activation of holmium poly(L-lactic acid) microspheres for hepatic arterial radioembolization: a validation study

M. A. D. Vente, J. F. W. Nijsen, R. de Roos, M. J. van Steenbergen, C. N. J. Kaaijk, M. J. J. Koster-Ammerlaan, P. F. A. de Leege, W. E. Hennink, A. D. van het Schip, G. C. Krijger

Journal:

Biomedical Microdevices

Year:

2009

Language:

english

File:

PDF, 332 KB

english, 2009

3

Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs

De Buck, S. S., Sinha, V. K., Fenu, L. A., Nijsen, M. J., Mackie, C. E., Gilissen, R. A. H. J.

Journal:

Drug Metabolism and Disposition

Year:

2007

Language:

english

File:

PDF, 452 KB

english, 2007

4

Clinical effects of transcatheter hepatic arterial embolization with holmium-166 poly(l-lactic acid) microspheres in healthy pigs

M. A. D. Vente, J. F. W. Nijsen, T. C. de Wit, J. H. Seppenwoolde, G. C. Krijger, P. R. Seevinck, A. Huisman, B. A. Zonnenberg, T. S. G. A. M. van den Ingh, A. D. van het Schip

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2008

Language:

english

File:

PDF, 486 KB

english, 2008

5

A model of heart rate changes to detect seizures in severe epilepsy

Wouter J.C. van Elmpt, Tamara M.E. Nijsen, Paul A.M. Griep, Johan B.A.M. Arends

Journal:

Year:

2006

Language:

english

File:

PDF, 493 KB

english, 2006

6

Better Business Regulation in a Risk Society ||

Alemanno, Alberto, den Butter, Frank, Nijsen, André, Torriti, Jacopo

Year:

2013

Language:

english

File:

PDF, 3.12 MB

english, 2013

7

Factors Affecting the Sensitivity and Detection Limits of MRI, CT, and SPECT for Multimodal Diagnostic and Therapeutic Agents

Seevinck, Peter, Seppenwoolde, Jan-Henry, de Wit, Tim, W. Nijsen, Johannes, Beekman, Freek, van het Schip, Alfred, G. Bakker, Chris

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 684 KB

english, 2007

8

Production of novel diagnostic radionuclides in small medical cyclotrons

Synowiecki, Mateusz Adam, Perk, Lars Rutger, Nijsen, J. Frank W.

Journal:

EJNMMI Radiopharmacy and Chemistry

Year:

2018

Language:

english

File:

PDF, 895 KB

english, 2018

9

Characterization of holmium loaded alginate microspheres for multimodality imaging and therapeutic applications

S.W. Zielhuis, J.H. Seppenwoolde, C.J.G. Bakker, U. Jahnz, B.A. Zonnenberg, A.D. van het Schip, W.E. Hennink, J.F.W. Nijsen

Journal:

Journal of Biomedical Materials Research Part A

Year:

2007

Language:

english

File:

PDF, 197 KB

english, 2007

10

Fully MR-guided hepatic artery catheterization for selective drug delivery: A feasibility study in pigs

Jan-Henry Seppenwoolde, Lambertus W. Bartels, Remko van der Weide, Johannes F.W. Nijsen, Alfred D. van het Schip, Chris J.G. Bakker

Journal:

Journal of Magnetic Resonance Imaging

Year:

2006

Language:

english

File:

PDF, 479 KB

english, 2006

11

Internal radiation therapy of liver tumors: Qualitative and quantitative magnetic resonance imaging of the biodistribution of holmium-loaded microspheres in animal models

Jan-Henry Seppenwoolde, Johannes F. W. Nijsen, Lambertus W. Bartels, Sander W. Zielhuis, Alfred D. van het Schip, Chris J. G. Bakker

Journal:

Magnetic Resonance in Medicine

Year:

2005

Language:

english

File:

PDF, 569 KB

english, 2005

12

FID sampling superior to spin-echo sampling for T-based quantification of holmium-loaded microspheres: Theory and experiment

Peter R. Seevinck, Jan-Henry Seppenwoolde, Jaco J.M. Zwanenburg, Johannes F.W. Nijsen, Chris J.G. Bakker

Journal:

Magnetic Resonance in Medicine

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

13

Production of GMP-grade radioactive holmium loaded poly(l-lactic acid) microspheres for clinical application

S.W. Zielhuis, J.F.W. Nijsen, R. de Roos, G.C. Krijger, P.P. van Rijk, W.E. Hennink, A.D. van het Schip

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 199 KB

english, 2006

14

Surface characteristics of holmium-loaded poly(l-lactic acid) microspheres

S.W. Zielhuis, J.F.W. Nijsen, R. Figueiredo, B. Feddes, A.M. Vredenberg, A.D. van het Schip, W.E. Hennink

Journal:

Year:

2005

Language:

english

File:

PDF, 318 KB

english, 2005

15

Long-term toxicity of holmium-loaded poly(l-lactic acid) microspheres in rats

Sander W. Zielhuis, J. Frank W. Nijsen, Jan-Henry Seppenwoolde, Chris J.G. Bakker, Gerard C. Krijger, Hub F.J. Dullens, Bernard A. Zonnenberg, Peter P. van Rijk, Wim E. Hennink, Alfred D. van het Schi

Journal:

Year:

2007

Language:

english

File:

PDF, 1.46 MB

english, 2007

16

5-Sulfonyl-benzimidazoles as selective CB2 agonists

Bie M.P. Verbist, Michel A.J. De Cleyn, Michel Surkyn, Erwin Fraiponts, Jeroen Aerssens, Marjoleen J.M.A. Nijsen, Harrie J.M. Gijsen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 217 KB

english, 2008

17

Unilateral intracarotid injection of holmium microspheres to induce bilateral MRI-validated cerebral embolization in rats

Fellery de Lange, Jan M. Dieleman, Erwin L.A. Blezer, Ralph J.F. Houston, Cor J. Kalkman, J. Frank W. Nijsen

Journal:

Journal of Neuroscience Methods

Year:

2009

Language:

english

File:

PDF, 429 KB

english, 2009

18

Characterization of poly(l-lactic acid) microspheres loaded with holmium acetylacetonate

J.F.W Nijsen, M.J van Steenbergen, H Kooijman, H Talsma, L.M.J Kroon-Batenburg, M van de Weert, P.P van Rijk, A de Witte, A.D van het Schip, W.E Hennink

Journal:

Year:

2001

Language:

english

File:

PDF, 361 KB

english, 2001

19

Influence of neutron irradiation on holmium acetylacetonate loaded poly(l-lactic acid) microspheres

J.F.W Nijsen, A.D van het Schip, M.J van Steenbergen, S.W Zielhuis, L.M.J Kroon-Batenburg, M van de Weert, P.P van Rijk, W.E Hennink

Journal:

Year:

2002

Language:

english

File:

PDF, 225 KB

english, 2002

20

Cisplatin-induced autonomic neuropathy: does it really exist?

W. P. Vandertop, W. B. Vries, N. C. Notermans, M. J. M. A. Nijsen, D. J. Wildt, C. A. F. Tulleken, W. H. Gispen

Journal:

Journal of Neuro-Oncology

Year:

1996

Language:

english

File:

PDF, 625 KB

english, 1996

21

Holmium-166 poly lactic acid microspheres applicable for intra-arterial radionuclide therapy of hepatic malignancies: effects of preparation and neutron activation techniques

J. F. W. Nijsen, B. A. Zonnenberg, J. R. W. Woittiez, D. W. Rook, I. A. Swildens-van Woudenberg, P. P. van Rijk, A. D. van het Schip

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1999

Language:

english

File:

PDF, 208 KB

english, 1999

22

Technical Solutions to Ensure Safe Yttrium-90 Radioembolization in Patients With Initial Extrahepatic Deposition of99mTechnetium–Albumin Macroaggregates

M. W. Barentsz, M. A. D. Vente, M. G. E. H. Lam, M. L. J. Smits, J. F. W. Nijsen, B. A. Seinstra, C. E. N. M. Rosenbaum, H. M. Verkooijen, B. A. Zonnenberg, M. A. A. J. Van den Bosch

Journal:

CardioVascular and Interventional Radiology

Year:

2011

Language:

english

File:

PDF, 217 KB

english, 2011

23

Cardio-vascular safety beyond hERG:in silicomodelling of a guinea pig right atrium assay

Luca A. Fenu, Ard Teisman, Stefan S. De Buck, Vikash K. Sinha, Ron A. H. J. Gilissen, Marjoleen J. M. A. Nijsen, Claire E. Mackie, Wendy E. Sanderson

Journal:

Journal of Computer-Aided Molecular Design

Year:

2009

Language:

english

File:

PDF, 440 KB

english, 2009

24

Microspheres with Ultrahigh Holmium Content for Radioablation of Malignancies

W. Bult, P. R. Seevinck, G. C. Krijger, T. Visser, L. M. J. Kroon-Batenburg, C. J. G. Bakker, W. E. Hennink, A. D. van het Schip, J. F. W. Nijsen

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 247 KB

english, 2009

25

Holmium Nanoparticles: Preparation andIn VitroCharacterization of a New Device for Radioablation of Solid Malignancies

Wouter Bult, Rosanne Varkevisser, Fouad Soulimani, Peter R. Seevinck, Hendrik de Leeuw, Chris J. G. Bakker, Peter R. Luijten, Alfred D. van het Schip, Wim E. Hennink, J. Frank W. Nijsen

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

26

Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release

Chris Oerlemans, Wouter Bult, Mariska Bos, Gert Storm, J. Frank W. Nijsen, Wim E. Hennink

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 690 KB

english, 2010

27

Radioactive Holmium Acetylacetonate Microspheres for Interstitial Microbrachytherapy: AnIn VitroandIn VivoStability Study

Wouter Bult, Hendrik de Leeuw, Olav M. Steinebach, Martijn J. van der Bom, Hubert Th. Wolterbeek, Ron M. A. Heeren, Chris J. G. Bakker, Alfred D. van het Schip, Wim E. Hennink, J. Frank W. Nijsen

Journal:

Pharmaceutical Research

Year:

2012

Language:

english

File:

PDF, 576 KB

english, 2012

28

Divergent role for CRF1 and CRF2 receptors in the modulation of visceral pain

M. Nijsen, N. Ongenae, A. Meulemans, B. Coulie

Journal:

Neurogastroenterology & Motility

Year:

2005

Language:

english

File:

PDF, 249 KB

english, 2005

29

Relevance of the C-terminal Arg-Phe sequence in γ2-melanocyte-stimulating hormone (γ2-MSH) for inducing cardiovascular effects in conscious rats

M J M A Nijsen, G J W De Ruiter, C M Kasbergen, P Hoogerhout, D J De Wildt

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 149 KB

english, 2000

30

Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis

M. A. D. Vente, M. Wondergem, I. van der Tweel, M. A. A. J. van den Bosch, B. A. Zonnenberg, M. G. E. H. Lam, A. D. van het Schip, J. F. W. Nijsen

Journal:

European Radiology

Year:

2009

Language:

english

File:

PDF, 142 KB

english, 2009

31

Holmium-166 poly(L-lactic acid) microsphere radioembolisation of the liver: technical aspects studied in a large animal model

M. A. D. Vente, T. C. de Wit, M. A. A. J. van den Bosch, W. Bult, P. R. Seevinck, B. A. Zonnenberg, H. W. A. M. de Jong, G. C. Krijger, C. J. G. Bakker, A. D. van het Schip, J. F. W. Nijsen

Journal:

European Radiology

Year:

2010

Language:

english

File:

PDF, 263 KB

english, 2010

32

5-Sulfonyl-benzimidazoles as selective CB2 agonists-Part 2

Harrie J.M. Gijsen, Michel A.J. De Cleyn, Michel Surkyn, Guy R.E. Van Lommen, Bie M.P. Verbist, Marjoleen J.M.A. Nijsen, Theo Meert, Jean Van Wauwe, Jeroen Aerssens

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

33

Microsatellite Analysis of Voided-Urine Samples for Surveillance of Low-Grade Non-Muscle-Invasive Urothelial Carcinoma: Feasibility and Clinical Utility in a Prospective Multicenter Study (Cost-Effectiveness of Follow-Up of Urinary Bladder Cancer Trial [CEFUB])

Madelon N.M. van der Aa, Ellen C. Zwarthoff, Ewout W. Steyerberg, Merel W. Boogaard, Yvette Nijsen, Kirstin A. van der Keur, Antonius J.A. van Exsel, Wim J. Kirkels, Chris Bangma, Theo H. van der Kwas

Journal:

European Urology

Year:

2009

Language:

english

File:

PDF, 668 KB

english, 2009

34

New model for intravenous drug administration and blood sampling in the awake rat, designed to increase quality and throughput for in vivo pharmacokinetic analysis

Claire Mackie, Koen Wuyts, Marc Haseldonckx, Saskia Blokland, Petra Gysemberg, Iris Verhoeven, Philip Timmerman, Marjoleen Nijsen

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

35

Role of corticotropin-releasing factor, vasopressin and the autonomic nervous system in learning and memory

Gerda Croiset, Marjoleen J.M.A Nijsen, Patrick J.G.H Kamphuis

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 100 KB

english, 2000

36

Endogenous corticotropin-releasing hormone inhibits conditioned-fear-induced vagal activation in the rat

Marjoleen J.M.A Nijsen, Gerda Croiset, Michaela Diamant, Rianne Stam, Patrick J.G.H Kamphuis, Adrie Bruijnzeel, David de Wied, Victor M Wiegant

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 192 KB

english, 2000

37

CRH Signalling in the Bed Nucleus of the Stria Terminalis is Involved in Stress-Induced Cardiac Vagal Activation in Conscious Rats

Marjoleen J.M.A Nijsen, Gerda Croiset, Michaela Diamant, David De Wied, Victor M Wiegant

Journal:

Neuropsychopharmacology

Year:

2001

Language:

english

File:

PDF, 361 KB

english, 2001

38

The Role of the CRH Type 1 Receptor in Autonomic Responses to Corticotropin- Releasing Hormone in the Rat

Marjoleen J.M.A Nijsen, Gerda Croiset, Ruben Stam, Adrie Bruijnzeel, Michaela Diamant, David de Wied, Victor M Wiegant

Journal:

Neuropsychopharmacology

Year:

2000

Language:

english

File:

PDF, 323 KB

english, 2000

39

Detection of Subtle Nocturnal Motor Activity From 3-D Accelerometry Recordings in Epilepsy Patients

Nijsen, T.M.E., Cluitmans, P.J.M., Arends, J.B.A.M., Griep, P.A.M.

Journal:

IEEE Transactions on Biomedical Engineering

Year:

2007

Language:

english

File:

PDF, 678 KB

english, 2007

40

Time-Frequency Analysis of Accelerometry Data for Detection of Myoclonic Seizures

Nijsen, T.M.E., Aarts, R.M., Cluitmans, P.J.M., Griep, P.A.M.

Journal:

IEEE Transactions on Information Technology in Biomedicine

Year:

2010

Language:

english

File:

PDF, 340 KB

english, 2010

41

An evaluation of the global potential of bioenergy production on degraded lands

Michiel Nijsen, Edward Smeets, Elke Stehfest, Detlef P. van Vuuren

Journal:

Year:

2012

Language:

english

File:

PDF, 786 KB

english, 2012

42

PVH lesions do not inhibit stressor-induced grooming in the rat

A.M.M. van Erp, M.R. Kruk, D.C. Willekens-Bramer, P.C.J. Fermont, M.J.M.A. Nijsen

Journal:

Physiology & Behavior

Year:

1995

Language:

english

File:

PDF, 581 KB

english, 1995

43

A novel approach to identify non-palpable breast lesions combining fluorescent liposomes and magnetic resonance-guided high intensity focused ultrasound-triggered release

Chris Oerlemans, Frank Nijsen, Miranda van Amersfoort, Louis van Bloois, Edwin Heijman, Peter Luijten, Willem Mali, Gert Storm

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2011

Language:

english

File:

PDF, 777 KB

english, 2011

44

The potential value of three-dimensional accelerometry for detection of motor seizures in severe epilepsy

Tamara M.E. Nijsen, Johan B.A.M. Arends, Paul A.M. Griep, Pierre J.M. Cluitmans

Journal:

Epilepsy & Behavior

Year:

2005

Language:

english

File:

PDF, 1.39 MB

english, 2005

45

Vagal Activation in Novelty-Induced Tachycardia During the Light Phase in the Rat

M.J.M.A Nijsen, G Croiset, M Diamant, M.H Broekhoven, D De Wied, V.M Wiegant

Journal:

Physiology & Behavior

Year:

1998

Language:

english

File:

PDF, 134 KB

english, 1998

46

Telemetric animal model to evaluate visceral pain in the freely moving rat

M.J.M.A Nijsen, N.G.H Ongenae, B Coulie, A.L Meulemans

Journal:

Year:

2003

Language:

english

File:

PDF, 184 KB

english, 2003

47

Intra-arterial embolization of head-and-neck cancer with radioactive holmium-166 poly(L-lactic acid) microspheres: an experimental study in rabbits

R.J.J. van Es, J.F.W. Nijsen, A.D. van het Schip, H.F.J. Dullens, P.J. Slootweg, R. Koole

Journal:

International Journal of Oral & Maxillofacial Surgery

Year:

2001

Language:

english

File:

PDF, 216 KB

english, 2001

48

The evolution of radioembolisation

Maarten LJ Smits, Maurice AAJ van den Bosch, Johannes FW Nijsen, Bernard A Zonnenberg

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 33 KB

english, 2012

49

Magnetic Resonance Imaging-Based Radiation-Absorbed Dose Estimation of 166Ho Microspheres in Liver Radioembolization

Peter R. Seevinck, Gerrit H. van de Maat, Tim C. de Wit, Maarten A.D. Vente, Johannes F.W. Nijsen, Chris J.G. Bakker

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2012

Language:

english

File:

PDF, 942 KB

english, 2012

50

Conditioned fear-induced tachycardia in the rat; vagal involvement

Marjoleen J.M.A Nijsen, Gerda Croiset, Michaela Diamant, Ruben Stam, Dianne Delsing, David de Wied, Victor M Wiegant

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 271 KB

english, 1998